The former Bills’ player issued a statement Thursday morning:

As our family has faced many trials and triumphs throughout the years, you have blessed us with your prayers. We are asking for those prayers once again. The oral cancer we hoped would be gone forever has returned. Although I was shocked and deeply saddened to receive this news, I know that God is with me. I continuously talk about the four F’s. Faith, Family, Friends and Fans. With all of you by my side, we will fight and win this battle together. Staying “Kelly Tough” and trusting God, will carry us through this difficult time.

Jim Kelly had been cancer-free since September 2014 after beating oral cancer that was first diagnosed in 2013.